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Showing 1 to 12 of 3285 entries
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Determination of the Presence of Three Antimicrobials in Surface Water Collected from Urban and Rural Areas.

Antibiotics (Basel, Switzerland)

Iglesias A, Nebot C, Miranda JM, Vázquez BI, Abuín CM, Cepeda A.
PMID: 27029291
Antibiotics (Basel). 2013 Feb 07;2(1):46-57. doi: 10.3390/antibiotics2010046.

Due to the continuous release of antimicrobials into the environment, the aim of this study was to compare the frequency of detection of sulfamethazine, sulfamethoxypyridazine and trimethoprim in surface water collected from urban and rural areas in Northwestern Spain....

Virulence of Acinetobacter baumannii Exhibiting Phenotypic Heterogeneous Growth against Meropenem in a Murine Thigh Infection Model.

Antibiotics (Basel, Switzerland)

Neou E, Michail G, Tsakris A, Pournaras S.
PMID: 27029293
Antibiotics (Basel). 2013 Mar 11;2(1):73-82. doi: 10.3390/antibiotics2010073.

Acinetobacter baumannii may exhibit phenotypic heterogeneous growth under exposure to antibiotics. We investigated the in vitro characteristics of A. baumannii isolates grown heterogeneously in the presence of meropenem and their virulence evaluated in experimental infections treated with meropenem. Five...

Molecular Mechanisms and Clinical Impact of Acquired and Intrinsic Fosfomycin Resistance.

Antibiotics (Basel, Switzerland)

Castañeda-García A, Blázquez J, Rodríguez-Rojas A.
PMID: 27029300
Antibiotics (Basel). 2013 Apr 16;2(2):217-36. doi: 10.3390/antibiotics2020217.

Bacterial infections caused by antibiotic-resistant isolates have become a major health problem in recent years, since they are very difficult to treat, leading to an increase in morbidity and mortality. Fosfomycin is a broad-spectrum bactericidal antibiotic that inhibits cell...

Synthesis and Immunological Evaluation of Virus-Like Particle-Milbemycin A₃/A₄ Conjugates.

Antibiotics (Basel, Switzerland)

Zeltins A, Turks M, Skrastina D, Lugiņina J, Kalnciema I, Balke I, Bizdēna Ē, Skrivelis V.
PMID: 28892001
Antibiotics (Basel). 2017 Sep 11;6(3). doi: 10.3390/antibiotics6030018.

Milbemycins are macrolide antibiotics with a broad spectrum of nematocidal, insecticidal, and acaricidal activity. To obtain milbemycin A₃/A₄ derivatives suitable for chemical conjugation to protein carriers (milbemycin haptens), succinate linker and a novel 17-atom-long linker containing a terminal carboxylic...

The Peptidoglycan Pattern of Staphylococcus carnosus TM300-Detailed Analysis and Variations Due to Genetic and Metabolic Influences.

Antibiotics (Basel, Switzerland)

Deibert J, Kühner D, Stahl M, Koeksoy E, Bertsche U.
PMID: 27669322
Antibiotics (Basel). 2016 Sep 23;5(4). doi: 10.3390/antibiotics5040033.

The Gram-positive bacterium Staphylococcus carnosus (S. carnosus) TM300 is an apathogenic staphylococcal species commonly used in meat starter cultures. As with all Gram-positive bacteria, its cytoplasmic membrane is surrounded by a thick peptidoglycan (PGN) or murein sacculus consisting of...

Protein Expression Modifications in Phage-Resistant Mutants of Aeromonas salmonicida after AS-A Phage Treatment.

Antibiotics (Basel, Switzerland)

Moreirinha C, Osório N, Pereira C, Simões S, Delgadillo I, Almeida A.
PMID: 29518018
Antibiotics (Basel). 2018 Mar 08;7(1). doi: 10.3390/antibiotics7010021.

The occurrence of infections by pathogenic bacteria is one of the main sources of financial loss for the aquaculture industry. This problem often cannot be solved with antibiotic treatment or vaccination. Phage therapy seems to be an alternative environmentally-friendly...

Small Molecule Docking Supports Broad and Narrow Spectrum Potential for the Inhibition of the Novel Antibiotic Target Bacterial Pth1.

Antibiotics (Basel, Switzerland)

Ferguson PP, Holloway WB, Setzer WN, McFeeters H, McFeeters RL.
PMID: 27171117
Antibiotics (Basel). 2016 May 10;5(2). doi: 10.3390/antibiotics5020016.

Peptidyl-tRNA hydrolases (Pths) play ancillary yet essential roles in protein biosynthesis by recycling peptidyl-tRNA. In E. coli, inhibition of bacterial Pth1 leads to accumulation of peptidyl-tRNA, depletion of aminoacyl-tRNA, and cell death. Eukaryotes have multiple Pths and Pth1 knock...

Reconsultation and Antimicrobial Treatment of Urinary Tract Infection in Male and Female Patients in General Practice.

Antibiotics (Basel, Switzerland)

Tandan M, Duane S, Cormican M, Murphy AW, Vellinga A.
PMID: 27649253
Antibiotics (Basel). 2016 Sep 15;5(3). doi: 10.3390/antibiotics5030031.

Current antimicrobial prescribing guidelines indicate that male and female patients with urinary tract infections (UTIs) should be treated with same antimicrobials but for different durations. The aim of this study was to explore the differences in reconsultations and antimicrobial...

Choline Binding Proteins from Streptococcus pneumoniae: A Dual Role as Enzybiotics and Targets for the Design of New Antimicrobials.

Antibiotics (Basel, Switzerland)

Maestro B, Sanz JM.
PMID: 27314398
Antibiotics (Basel). 2016 Jun 14;5(2). doi: 10.3390/antibiotics5020021.

Streptococcus pneumoniae (pneumococcus) is an important pathogen responsible for acute invasive and non-invasive infections such as meningitis, sepsis and otitis media, being the major cause of community-acquired pneumonia. The fight against pneumococcus is currently hampered both by insufficient vaccine...

Pharmacokinetic/Toxicity Properties of the New Anti-Staphylococcal Lead Compound SK-03-92.

Antibiotics (Basel, Switzerland)

Schwan WR, Kolesar JM, Kabir MS, Elder EJ, Williams JB, Minerath R, Cook JM, Witzigmann CM, Monte A, Flaherty T.
PMID: 26877886
Antibiotics (Basel). 2015 Dec;4(4):617-626. doi: 10.3390/antibiotics4040617. Epub 2015 Nov 24.

Because of the potential of a new anti-staphylococcal lead compound SK-03-92 as a topical antibiotic, a patch, or an orally active drug, we sought to determine its safety profile and oral bioavailability. SK-03-92 had a high IC

Advances in Antarctic Research for Antimicrobial Discovery: A Comprehensive Narrative Review of Bacteria from Antarctic Environments as Potential Sources of Novel Antibiotic Compounds Against Human Pathogens and Microorganisms of Industrial Importance.

Antibiotics (Basel, Switzerland)

Núñez-Montero K, Barrientos L.
PMID: 30347637
Antibiotics (Basel). 2018 Oct 19;7(4). doi: 10.3390/antibiotics7040090.

The recent emergence of antibiotic-resistant bacteria has become a critical public health problem. It is also a concern for industries, since multidrug-resistant microorganisms affect the production of many agricultural and food products of economic importance. Therefore, discovering new antibiotics...

The State of Education and Training for Antimicrobial Stewardship Programs in Indian Hospitals-A Qualitative and Quantitative Assessment.

Antibiotics (Basel, Switzerland)

Singh S, Charani E, Wattal C, Arora A, Jenkins A, Nathwani D.
PMID: 30704037
Antibiotics (Basel). 2019 Jan 30;8(1). doi: 10.3390/antibiotics8010011.

No abstract available.

Showing 1 to 12 of 3285 entries